Primary Renal Synovial Sarcoma

Synovial sarcomas are generally deep-seated tumors that most often occur in the proximity of large joints of adolescents and young adults. We describe two cases of primary renal synovial sarcoma that were treated successfully by radical nephrectomy. Synovial sarcoma originating from the kidney is extremely rare and the histogenesis is uncertain. Surgical resection and ifosfamide based chemotherapy are the mainstay for the management of renal synovial sarcoma. Fewer than 40 patients have been described in the English literature. Physicians should be aware of the possibility of malignancy in cystic renal masses and raise the suspicion of synovial sarcoma, especially when patients with renal masses are a young adult

Acute effect of phosphodiesterase type 5 inhibitor on serum oxidative status and prolidase activities in men with erectile dysfunction

OBJECTIVES: To investigate the acute effect of phosphodiesterase type 5 (PDE5) inhibitor on erectile dysfunction by evaluating serum oxidative status and prolidase activity. METHODS: Serum samples of 36 patients with erectile dysfunction and 30 control cases were analyzed for total antioxidant status, total oxidant status, and prolidase activity, before and after the administration of tadalafil citrate. RESULTS: Before and after tadalafil citrate administration, serum total antioxidant status, total oxidant status, and prolidase were 1.1+0.0 vs. 1.6 + 0.0 umol H2O2 Eq/L, 10.3+1.1 vs. 6.9 + 1.2 umol H2O2 Eq/L, and 236.4+19.5 vs. 228.2 + 19.2 U/L, respectively (

Tuberculous Epididymitis Mimicking a Testicular Tumour: A Case Report

Tuberculosis is a disease that affects almost every organ. The diagnosis and treatment of primary genitourinary tuberculosis is cumbersome and often requires invasive procedures for diagnosis. It is mandatory to differentiate tuberculous epididymitis from other causes of intrascrotal diseases such as bacterial epididiymitis and tumors. We discussed a case of tuberculous epididymitis presenting with a scrotal mass, to emphasize that tuberculous should also be considered in the differential diagnosis, besides malignanc

Hematolojik Parametrelerin Prostat Biyopsisi Sonuçlarını Öngörmede Önemli Bir Rolü Var mı?

Objective: To assess the predictive role of hematological parameters on the results of prostate biopsies. Method: We evaluated patients who underwent ultrasound-guided prostate biopsies between January 2014 and April 2016. The patients were divided into two groups according to their histopathological results: as patients with and without established diagnosis of prostate cancer. White blood cell, neutrophil, lymphocyte, platelet counts, hemoglobin level, hematocrit, red cell distribution width, mean platelet volume, platelet distribution width and plateletcrit were analyzed before biopsy. Additionally, neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios were calculated. These parameters were compared between the two groups and statistically analyzed. Results: Prostate cancer was detected in 38 (30.25%) patients, and benign conditions (prostatic hyperplasia or chronic prostatitis) were detected in 88 (69.85%) patients. There was no statistically significant difference between the patients with prostate cancer and patients with benign conditions according to the white blood cell, neutrophil, lymphocyte, platelet counts, hemoglobin level, hematocrit, red cell distribution width, mean platelet volume and platelet distribution width and plateletcrit. Additionally, there were no statistically significant differences between the groups regarding the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios. Conclusion: Hematological parameters do not play a significant role in predicting prostate biopsy results. More sophisticated studies are needed to further evaluate this issue.Amaç: Hematolojik parametrelerin prostat biyopsisi sonuçları üzerindeki öngörücü rolünü değerlendirmek Yöntem: Ocak 2014-Nisan 2016 tarihleri arasında ultrason eşliğinde prostat biyopsisi yapılan hastaları değerlendirdik. Hastalar histopatolojik sonuçlarına göre iki gruba ayrıldı: prostat kanseri saptanan ve saptanmamış hastalar. Biyopsi öncesi eritrosit sayısı, nötrofil sayısı, lenfosit sayısı, trombosit sayısı, hemoglobin düzeyi, hematokrit, kırmızı hücre dağılım genişliği, ortalama trombosit hacmi, trombosit dağılım genişliği ve trombosit incelemesi yapıldı. Ek olarak, nötrofil lenfosit oranları ve trombosit lenfosit oranları hesaplandı. Bu parametreler iki grup arasında karşılaştırıldı ve istatistiksel olarak analiz edildi. Bulgular: Prostat kanseri 38 hastada (%30,25) ve benign prostat hastalıkları (prostat hiperplazisi veya kronik prostatit) 88 hastada (%69,85) tespit edildi. Prostat kanserli hastalar ile eritrosit sayısı, nötrofil sayısı, lenfosit sayısı, trombosit sayısı, hemoglobin düzeyi, hematokrit,eritrosit dağılım genişliği, ortalama trombosit hacmi ve trombosit dağılımı genişliği açısından benign durumları olan hastalar arasında istatistiksel olarak anlamlı bir fark yoktu. Ek olarak, gruplar arasında nötrofil/lenfosit oranı ve trombosit/lenfosit oranı açısından istatistiksel olarak anlamlı bir fark yoktu. Sonuç: Hematolojik parametreler prostat biyopsi sonuçlarını öngörmede önemli bir rol oynamaz. Bu konunun daha fazla değerlendirilmesi için daha ileri çalışmalara ihtiyaç vardır

Experience and learning curve of retroperitoneal laparoscopic ureterolithotomy

This study was conducted to evaluate clinical experience and learning curve associated with laparoscopic ureterolithotomy performed for upper ureteral stones. The medical data of 50 patients who had undergone retroperitoneal laparoscopic ureterolithotomy between June 2010 and March 2013 were retrospectively analyzed. To assess the learning curve, patients were divided into two groups: Group A (the first 25 cases) and Group B (the last 25 cases). In Group A, double J stents were placed in 17 patients, whereas in Group B 15 patients received double J stents. In Group A, three ports were placed in nine patients and four ports in 16 patients. In Group B, three ports were placed in 20 patients and five patients had four ports. The patients were compared according to demographics, operative time, stone size, complications, hospital stay, and transfusion. The mean age for Group A was 47.8 ± 14.13 (21–72) years and that for Group B was 44.2 ± 14.98 (22–78) years. Mean operative times were 106.4 ± 38 (55–210) minutes and 70.76 ± 30.4 (30–180) minutes for Groups A and B, respectively (p 0.05). In our study, as staff experience (in performing laparoscopic retroperitoneal ureterolithotomy) increased, operative time, length of hospital stay, and complication rates have correspondingly declined

Better outcomes with desmopressin melt than enuretic alarm therapy in children with nocturnal enuresis during coronavirus disease 2019 (COVID-19)

Abstract. Objectives:. This study aimed to investigate the effect of the coronavirus disease 2019 (COVID-19) pandemic on the treatment of children with primary monosymptomatic nocturnal enuresis (MNE) with desmopressin melt versus an enuresis alarm. Materials and methods:. This study included 56 children with primary MNE who were taking desmopressin melt or using an alarm. Their anxiety levels were evaluated using the Social Anxiety Scale for Children-Revised. For both treatment methods, data from a 3-month bedwetting diary between the third and sixth months of the pre-pandemic treatment were compared with those assessed during the same period during the pandemic. Results:. Prior to the COVID-19 pandemic, the median 3-month mean frequency of MNE was 1 (0–7.67) in children using desmopressin melt versus 1.33 (0–6) in those using alarm treatment (p = 0.095). During the COVID-19 pandemic period, the median monthly mean frequency of MNE was 1.33 (0–7.33) in children using desmopressin melt versus 6 (1.33–13) in those using alarm treatment (p < 0.001). Conclusions:. The COVID-19 pandemic and its accompanying psychological effects did not affect the treatment efficacy of desmopressin melt in children with primary MNE but did adversely affect that of enuresis alarms

Effects of Laparoscopic Ureterolithotomy and Simultaneous Trans-Trocar Semi-Rigid Ureteroscopy on Stone-Free Rate in the Treatment of Proximal Ureteral Stones

WOS: 000218668400005Objective This study presents the effects of the use of semi-rigid ureteroscopy simultaneously during laparoscopic ureterolithotomy on the stone-free rate and, the techniques used to perform laparoscopic ureterolithotomy less invasively. Materials and Methods Between November 2011 and July 2013, laparoscopic ureterolithotomy was performed in 19 patients with proximal ureteral stones. A history of failed shock wave lithotripsy (SWL) or semi-rigid ureteroscopy (sr-URS), presence of ureter stones >= 15 mm and/or impacted stones, or a socioeconomic status not allowing the patient to reach an advanced center for flexible ureteroscopy (f-URS) were identified as the surgical indications. Results Fourteen male (74%) and five female (26%) patients were enrolled in the study and the mean age was 36.4 +/- 15.11 (15-70) years. The stones were located on right side in five patients (26%) and left side in 14 patients (74%). The mean stone size was 16.2 +/- 3.55 mm (8-22). The mean operation time was 138.9 +/- 29.56 minutes (90-200). The mean urethral catheter and drain removal time was 31.2 +/- 24.28 (16-120) and 50.8 +/- 33.61 hours (18-168), respectively. There was no postoperative complication in long-term period and stone-free rate was 100%. Conclusion Laparoscopic ureterolithotomy is a feasible alternative in a patient who had previously failed minimally invasive methods and/or with large impacted proximal ureteral stone. Furthermore, to use semi-rigid ureteroscopy during the laparoscopic procedure increases the stonefree rate and prevents the need for an additional procedure in case of concurrent presence of small kidney stones